Mastermind Popple, Baroness Popple and the Six Popplesmen head to Equestria and start destroying everything. They kill the Mane Six, forcing Princess Celestia to send Spike to go to the real world to send in a few people to save Equestria from destruction.
- Dave as WilliamWill2343
- Kayla as Sophie the Otter, Jelly Otter, Twilight Sparkle, Bonnie Wagner
- Eric as Billy Wagner, P.C. Popple
- David as Hamilton Koala
- Princess as Katherine Koala
- Brian as
- Kate as Party Popple
- Kimberly as Peanut Otter, Richard Raccoon, Rainbow Dash, Potato Chip Popple
- Julie as Amanda Panda, Pinkie Pie, Puffball Popple, Prize Popple
- Young Guy as Rogan Raccoon, Kevin Danires
- Shy Girl as Baby Butter Otter, Pretty Bit Popple
- Tween Girl as Shari Sunbeam, Emilia Caprice, Pancake Popple
- Susan as Fluttershy
- Emma as
- Catherine as Rarity
- Salli as Halley Wagner
- Belle as Applejack
- Simon as
- Professor as Puzzle Popple
- Wise Guy as Putter Popple
- Ivy as Melody, Sally Otter, Becky Bopper, Brenda Wagner, Rosellia McLaren Allison, Isabella Diego, Jennifer Koala, Spike,
[The company logos play]
[We see the words "WilliamWill Pictures presents", then we see "A Hasbro Studios, DHX Media, and Fireworks Pictures production"]
[We open on a view of Equestria]
[We see the Mane 6 in Friendship Rainbow Kingdom castle]
Twilight Sparkle: "It's going to be an exceptional day, my friends."
Pinkie: "Hooray! It'll be great!"
Rainbow Dash: "Let's get pumped for this!"
[Meanwhile in a forest near Ponyville]
[Evil laughing can be heard in a bush]
???: "The plan must work out p-p-perfectly!"
???: "It will, p-p-Popplesmen."
[They head to the Friendship Rainbow Castle]